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Louis H. Philipson Professor of Endocrinology, Department of Medicine and Committee on Cell Physiology Areas of Expertise:
John Easton |
Background:
Dr. Philipson's research focuses on how pancreatic Beta-cells "know" when to secrete insulin and define defects in this process in diabetes that could be therapeutic targets. His focus is the study of ion channels, metabolism, and mitochondria that together regulate intracellular calcium concentration and energy production and thereby regulate insulin secretion in pancreatic islet Beta-cells. He studies such processes as exocytosis of single insulin granules and production of reactive oxygen species in normal and diabetic mice and in human islets.
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News clippings:
Gene Mutations May Cause Rare Neonatal Diabetes WASHINGTON POST September 14, 2007 One girl, one story living on FDA Approves Insulin Device For Diabetics After Initial Rejection, Scientists Back Work On Cure for Diabetes A Controversial Therapy for Diabetes Is Verified |
Press releases:
Mutations in the insulin gene can cause neonatal diabetes Molecular medicine comes to the rescue: Targeted therapy turns life around for child with neonatal diabetes |
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Chronicle articles:
Chicago In the News September 20, 2007 |
Additional materials:
Website |
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